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TPS-10%

Tylosin phosphate-10% premix

As an aid in the control of nectrotic enteritis broiler, layer, breeder, and replacement chickens.

Composition:  1 kg of the TPS-10% contains 100gms of tylosin Phosphate

Benefits of TPS-10%

Tylosin phosphate belongs to the macrolide group. Tylosin phosphate is phosphate acid salt form of tylosin, which is a special animal antibiotic. It can prevent cross-resistance problems in common antibiotic between human and animal to common antibiotics.

The macrolide group is primarily active against gram positive bacteria such as staphylococcus and streptococcus spaecies, Including a number of organisms that are resistant to penicillins(due to beta-lactamase production). Tylosin is also active against some gram-negative bacteria(including campylobacter and pasteurella species) and has a useful activity against certainmycoplasmas (against which it is more effective than erythromycin, which in most other respects has a similar spectrum of activity).

Tylosin phosphate In feed is specifically indicated in cattle for prophylaxis against hepatic abscesses caused by fusobacterium necrophorum and actinomyces pyogenes.

In broilers chickens and laying hens in feed tylosin phosphate may be indicated for increased rate of gain and improved feed efficiency and is also indicated as an aid In the treatment of chronic respiratory diseases caused by susceptible Mycoplasma gallisepticum.

Tylosin inhibits bacterial protein synthesis by reversibly binding with to L27 protein of the 50S subunit of thebacterial ribosome whereby it inhibits translocation of tRNA from the peptidy (P)  site.

Adverse effects:

Tylosin may cause severe or even fatal gastrointestinal disturbance in horses.

The safely of tylosin in breeding animals has not been established.

Contraindications:

Tylosin should not be administered to horses. Tylosin may compete with chloramphenicol and lincosamides for the ribosomal binding site.

Health and safety:

Exposure to tylosin may cause irritation of skin and eyes. Avoid contact with skin and eyes. Harmful if swallowed. Repeated exposure may cause allergic disorders. Do not inhale dust. When handling the product wear protective clothing without exposing skin to product and use a dust face mask covering mouth and nose.

Please clear your hands thoroughly with soap and water after use of the product.

Dosage:

In Layers:( 50ppm )500gms per ton of finished feed form point of lay till 42nd week.( 20ppm )200gms per ton of finished feed from 43rd week till culling.

In Broilers:   (20ppm) 200gms per ton of finished feed from day 1 till 455th day.

In Breeders: (500ppm) 500gms per ton of finished feed from point of lay till culling.

Storage:

Store below 30c in a dry place

Packing:

1 kg, 25 kgs

Keep out of reach of children